Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.32 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5318494 | 0.81 | KDM4E (0.38) | GAAHTTLMNAMEN1KMT2A | |
| SCHEMBL5764364 | 0.74 | ABL1 (0.38) | GAAHTTLMNAMEN1KMT2A | |
| SCHEMBL21003314 | 0.72 | SMN1; SMN2 (0.36) | GAAMEN1KMT2AMAPTKDM4E | |
| SCHEMBL31682592 | 0.69 | HTT (0.36) | GAAHTTLMNAMEN1KMT2A | |
| SCHEMBL5759485 | 0.69 | ABL1 (0.35) | GAAHTTLMNAMAPTNPSR1 | |
| SCHEMBL7333342 | 0.68 | SMN1; SMN2 (0.40) | HTTLMNAMEN1KMT2AMAPT | |
| SCHEMBL27028859 | 0.68 | KDM4E (0.49) | GAALMNAMEN1KMT2AMAPT | |
| SCHEMBL21954978 | 0.67 | HTT (0.37) | GAAHTTLMNAMEN1KMT2A | |
| SCHEMBL10615281 | 0.67 | KDM4E (0.48) | GAALMNAMEN1KMT2ANPSR1 | |
| SCHEMBL4642069 | 0.66 | KDM4E (0.36) | LMNAMEN1KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5536733-A | GASTROINTESTINAL | JANSSEN PHARMACEUTICA N.V. (BE) | 1996-07-16 | — | — | US | disclosed |