SCHEMBL8943610

SCHEMBL8943610

COc1ccc(OCCOc2ccc(O)c(C(=O)O)c2)cc1.[Zn]

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.51
RAB9A P51151 3/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
POLB P06746 1/20 0.51
APEX1 P27695 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
MCL1 Q07820 2/20 0.51
SMN1; SMN2 Q16637 2/20 0.49
MAPT P10636 2/20 0.49
LMNA P02545 2/20 0.49
TP53 P04637 2/20 0.49
KDM4E B2RXH2 2/20 0.49
ALDH1A1 P00352 2/20 0.49
HPGD P15428 2/20 0.49
HSD17B10 Q99714 2/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
ALOX12 P18054 1/20 0.49
MTNR1A P48039 1/20 0.45
MTNR1B P49286 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9305720 0.98 NPC1 (0.52) NPC1RAB9AL3MBTL1POLBAPEX1
SCHEMBL9304812 0.94 MCL1 (0.54) NPC1RAB9AL3MBTL1POLBAPEX1
SCHEMBL9305419 0.94 MCL1 (0.54) NPC1RAB9AL3MBTL1POLBAPEX1
SCHEMBL26936 0.88 PPARD (0.55) NPC1RAB9AL3MBTL1POLBAPEX1
SCHEMBL8417746 0.88 MCL1 (0.53) NPC1RAB9AMCL1SMN1; SMN2MAPT
SCHEMBL9304663 0.86 CSNK2A1 (0.59) NPC1L3MBTL1POLBMCL1MAPT
SCHEMBL51025 0.86 PPARD (0.56) NPC1RAB9AL3MBTL1POLBAPEX1
SCHEMBL29378251 0.86 PPARD (0.56) NPC1RAB9AL3MBTL1POLBAPEX1
SCHEMBL13974898 0.86 IGF1R (0.55) TDP1MCL1MEN1KMT2A
SCHEMBL9003347 0.86 KLKB1 (0.62) NPC1RAB9AL3MBTL1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed