SCHEMBL8943978

SCHEMBL8943978

c1ccc(N(c2ccccc2)c2cccc(Oc3cccc(N(c4ccccc4)c4ccccc4)c3)c2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.48
LTA4H P09960 2/20 0.48
TSHR P16473 2/20 0.48
AKR1C3 P42330 1/20 0.44
ALDH1A1 P00352 2/20 0.43
MAPT P10636 2/20 0.43
KDM4E B2RXH2 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
CETP P11597 2/20 0.41
GRM2 Q14416 1/20 0.40
MEN1 O00255 1/20 0.40
MITF O75030 1/20 0.40
GAA P10253 1/20 0.40
GFER P55789 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16890151 0.98 MAOB (0.47) MAOBLTA4HTSHRAKR1C3ALDH1A1
SCHEMBL24119800 0.94 MAOB (0.44) MAOBLTA4HTSHRAKR1C3ALDH1A1
SCHEMBL21918077 0.94 MAOB (0.44) MAOBLTA4HTSHRAKR1C3ALDH1A1
SCHEMBL24119757 0.94 MAOB (0.44) MAOBLTA4HTSHRAKR1C3ALDH1A1
SCHEMBL24491415 0.92 MAOB (0.47) MAOBLTA4HTSHRAKR1C3ALDH1A1
SCHEMBL24400122 0.92 MAOB (0.47) MAOBLTA4HTSHRAKR1C3ALDH1A1
SCHEMBL23421390 0.92 MAOB (0.47) MAOBLTA4HTSHRAKR1C3ALDH1A1
SCHEMBL2623337 0.90 MAOB (0.41) MAOBLTA4HTSHRAKR1C3ALDH1A1
SCHEMBL23420965 0.90 MAOB (0.46) MAOBLTA4HTSHRAKR1C3ALDH1A1
SCHEMBL24106924 0.90 MAOB (0.48) MAOBLTA4HTSHRAKR1C3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed