Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | EDNRA | P25101 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4404392 | 0.77 | KMT2A (0.56) | KMT2AMEN1CYP1A2NPC1KDM4E | |
| SCHEMBL922692 | 0.77 | KMT2A (0.69) | KMT2AMEN1CYP1A2NPC1KDM4E | |
| SCHEMBL8119446 | 0.74 | KMT2A (0.65) | KMT2AMEN1CYP1A2NPC1KDM4E | |
| SCHEMBL13208586 | 0.74 | KMT2A (0.51) | KMT2AMEN1CYP1A2NPC1KDM4E | |
| SCHEMBL11463026 | 0.72 | KMT2A (0.63) | KMT2AMEN1CYP1A2NPC1KDM4E | |
| SCHEMBL8106855 | 0.72 | KMT2A (0.52) | KMT2AMEN1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL1060193 | 0.72 | CA12 (0.32) | — | |
| SCHEMBL281854 | 0.71 | RAF1 (0.41) | KMT2AMEN1NPC1KDM4EALDH1A1 | |
| SCHEMBL10630642 | 0.71 | KMT2A (0.61) | KMT2AMEN1CYP1A2NPC1KDM4E | |
| SCHEMBL20505093 | 0.71 | KMT2A (0.61) | KMT2AMEN1CYP1A2NPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541202-A | New leukotriene-B4 Antagonists and their use as pharmaceutical agents | SCHERING AKTIENGESELLSCAFT (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0597968-A1 | NEW LEUKOTRIENE-B 4? ANTAGONISTS, METHODS OF PREPARING THEM AND THEIR USE AS DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-05-25 | — | — | EP | disclosed |
| WO-1993004056-A1 | NEW LEUKOTRIENE-B4 ANTAGONISTS, METHODS OF PREPARING THEM AND THEIR USE AS DRUGS | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1993-03-04 | — | — | WO | disclosed |
| EP-0529749-A1 | Leukotriene-B4-antagonists, method for their preparation, and their use as medicaments | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-03-03 | — | — | EP | disclosed |