Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8944783 | 0.98 | EPHX1 (0.61) | EPHX1SMN1; SMN2ALDH1A1ALOX15TSHR | |
| SCHEMBL8944817 | 0.98 | EPHX1 (0.61) | EPHX1SMN1; SMN2ALDH1A1ALOX15TSHR | |
| Hydrochloric Acid SCHEMBL27795059 | 0.96 | EPHX1 (0.59) | EPHX1SMN1; SMN2ALDH1A1ALOX15TSHR | |
| SCHEMBL1133959 | 0.95 | — | — | |
| SCHEMBL15610128 | 0.90 | — | — | |
| SCHEMBL28303600 | 0.82 | EPHX1 (0.39) | EPHX1SMN1; SMN2ALDH1A1ALOX15TSHR | |
| SCHEMBL25283458 | 0.80 | EPHX1 (0.38) | EPHX1SMN1; SMN2HDAC1HDAC2HDAC3 | |
| SCHEMBL27645529 | 0.80 | CHRM3 (0.45) | EPHX1TSHRHDAC1HDAC2CYP3A4 | |
| SCHEMBL27762919 | 0.79 | EPHX1 (0.41) | EPHX1SMN1; SMN2ALDH1A1CYP3A4MAPT | |
| SCHEMBL28132612 | 0.79 | EPHX1 (0.37) | EPHX1SMN1; SMN2ALDH1A1ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103167867-A | Solid dispersions containing an apoptosis-inducing agent | ABBOTT LAB | 2013-06-19 | — | — | CN | disclosed |
| CN-103153993-A | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases | ABBOTT LAB | 2013-06-12 | — | — | CN | disclosed |
| US-5578731-A | ASYMMETRICAL HYDRAZINE DERIVATIVE | CIBA-GEIGY CORPORATION (US) | 1996-11-26 | — | — | US | disclosed |
| US-5554754-A | PHOTOSTABILIZERS | CIBA-GEIGY CORPORATION (US) | 1996-09-10 | — | — | US | disclosed |
| US-5470980-A | Light stabilizers for polymers that can be grafted to polymers | CIBA-GEIGY CORPORATION (US) | 1995-11-28 | — | — | US | disclosed |
| EP-0647626-A1 | Azadicarboxylic acid derivatives containing hindered amine moieties as polymer stabilisers | CIBA-GEIGY AG (CH) | 1995-04-12 | — | — | EP | disclosed |
| US-5352719-A | Blended with synthetic or natural polymers | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1994-10-04 | — | — | US | disclosed |
| US-5319090-A | Benzotriazole and oxanilide UV absorber hydrazides | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1994-06-07 | — | — | US | disclosed |
| US-5233047-A | Benzotriazole UV absorber hydrazides | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1993-08-03 | — | — | US | disclosed |
| US-5116976-A | HINDERED AMINE LIGHT STABILIZER HYDRAZIDES | ATOCHEM NORTH AMERICA, INC (US) | 1992-05-26 | — | — | US | disclosed |
| US-5041545-A | 2-hydroxybenzophenone hydrazides and derivatives thereof | ATOCHEM NORTH AMERICA, INC. (US) | 1991-08-20 | — | — | US | disclosed |
| US-4980420-A | Benzotriazole and oxanilide UV absorber hydrazides | ATOCHEM NORTH AMERICA, INC. (US) | 1990-12-25 | — | — | US | disclosed |