SCHEMBL8944905

SCHEMBL8944905

CCCCC(CC)COC(=O)NN

nearest known ligand 0.60

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.60
TSHR P16473 3/20 0.60
TDP1 Q9NUW8 3/20 0.60
ATM Q13315 1/20 0.60
ALDH1A1 P00352 6/20 0.53
CA2 P00918 5/20 0.53
LMNA P02545 3/20 0.50
HSD17B10 Q99714 1/20 0.50
RECQL P46063 1/20 0.50
CA1 P00915 2/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
MAPK1 P28482 2/20 0.47
PRSS1 P07477 1/20 0.47
PRSS2 P07478 1/20 0.47
PRSS3 P35030 1/20 0.47
MMP9 P14780 1/20 0.44
MMP8 P22894 1/20 0.44
MMP14 P50281 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL27745825 0.85 CYP3A4 (0.58) CYP3A4TSHRTDP1ATMALDH1A1
SCHEMBL11029516 0.84 CYP3A4 (0.62) CYP3A4TSHRTDP1ATMALDH1A1
Ammonia Solution, Strong SCHEMBL9998720 0.83 TSHR (0.57) CYP3A4TSHRTDP1ATMALDH1A1
SCHEMBL28611156 0.83 CYP3A4 (0.57) CYP3A4TSHRTDP1ATMALDH1A1
SCHEMBL28062999 0.83 CYP3A4 (0.60) CYP3A4TSHRTDP1ATMALDH1A1
Hydrochloric Acid SCHEMBL4867011 0.83 CYP3A4 (0.60) CYP3A4TSHRTDP1ATMALDH1A1
Ammonia Solution, Strong SCHEMBL23878442 0.82 CYP3A4 (0.64) CYP3A4TSHRTDP1ATMALDH1A1
Ammonia Solution, Strong SCHEMBL9998237 0.82 CYP3A4 (0.68) CYP3A4TSHRTDP1ATMALDH1A1
SCHEMBL11150821 0.81 CYP3A4 (0.58) CYP3A4TSHRTDP1ATMALDH1A1
SCHEMBL9702525 0.81 CYP3A4 (0.58) CYP3A4TSHRTDP1ATMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5578731-A ASYMMETRICAL HYDRAZINE DERIVATIVE CIBA-GEIGY CORPORATION (US) 1996-11-26 US disclosed
US-5554754-A PHOTOSTABILIZERS CIBA-GEIGY CORPORATION (US) 1996-09-10 US disclosed
US-5470980-A Light stabilizers for polymers that can be grafted to polymers CIBA-GEIGY CORPORATION (US) 1995-11-28 US disclosed
EP-0647626-A1 Azadicarboxylic acid derivatives containing hindered amine moieties as polymer stabilisers CIBA-GEIGY AG (CH) 1995-04-12 EP disclosed
US-5352719-A Blended with synthetic or natural polymers ELF ATOCHEM NORTH AMERICA, INC. (US) 1994-10-04 US disclosed
US-5319090-A Benzotriazole and oxanilide UV absorber hydrazides ELF ATOCHEM NORTH AMERICA, INC. (US) 1994-06-07 US disclosed
US-5233047-A Benzotriazole UV absorber hydrazides ELF ATOCHEM NORTH AMERICA, INC. (US) 1993-08-03 US disclosed
US-5116976-A HINDERED AMINE LIGHT STABILIZER HYDRAZIDES ATOCHEM NORTH AMERICA, INC (US) 1992-05-26 US disclosed
EP-0467344-A1 Hindered amine light stabilizer hydrazides ELF ATOCHEM NORTH AMERICA, INC. (US) 1992-01-22 EP disclosed
US-5041545-A 2-hydroxybenzophenone hydrazides and derivatives thereof ATOCHEM NORTH AMERICA, INC. (US) 1991-08-20 US disclosed
US-4980420-A Benzotriazole and oxanilide UV absorber hydrazides ATOCHEM NORTH AMERICA, INC. (US) 1990-12-25 US disclosed