SCHEMBL8944908

SCHEMBL8944908

CCCCCCCCCCc1cnc(-c2ccc(OCCCCCC(C)OCCCCC)cc2)nc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 5/20 0.54
RAB9A P51151 5/20 0.53
KDM4E B2RXH2 4/20 0.53
NPC1 O15118 3/20 0.53
ALDH1A1 P00352 4/20 0.51
SMN1; SMN2 Q16637 3/20 0.51
MAPT P10636 3/20 0.51
HPGD P15428 3/20 0.51
HSD17B10 Q99714 2/20 0.51
MEN1 O00255 2/20 0.51
USP2 O75604 2/20 0.51
KMT2A Q03164 2/20 0.51
GAA P10253 1/20 0.51
L3MBTL1 Q9Y468 2/20 0.45
CASP3 P42574 1/20 0.43
SENP8 Q96LD8 1/20 0.43
SENP7 Q9BQF6 1/20 0.43
SENP6 Q9GZR1 1/20 0.43
TP53 P04637 1/20 0.42
TSHR P16473 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9488868 1.00 RARB (0.54) RARBRAB9AKDM4ENPC1ALDH1A1
SCHEMBL9489010 1.00 RARB (0.54) RARBRAB9AKDM4ENPC1ALDH1A1
SCHEMBL9490681 1.00 RARB (0.54) RARBRAB9AKDM4ENPC1ALDH1A1
SCHEMBL9488401 1.00 RARB (0.54) RARBRAB9AKDM4ENPC1ALDH1A1
SCHEMBL9489359 1.00 RARB (0.54) RARBRAB9AKDM4ENPC1ALDH1A1
SCHEMBL9489189 1.00 RARB (0.54) RARBRAB9AKDM4ENPC1ALDH1A1
SCHEMBL9487948 0.98 RARB (0.54) RARBRAB9AKDM4ENPC1ALDH1A1
SCHEMBL9490239 0.98 RARB (0.54) RARBRAB9AKDM4ENPC1ALDH1A1
SCHEMBL9488214 0.95 RARB (0.54) RARBRAB9AKDM4ENPC1ALDH1A1
SCHEMBL9487339 0.95 RARB (0.54) RARBRAB9AKDM4ENPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5580489-A MIXING OPTICALLY ACTIVE AND INACTIVE COMPOUNDS CANON KABUSHIKI KAISHA (JP) 1996-12-03 US disclosed
US-5501818-A PYRIMIDINE COMPOUNDS, IMPROVED RESPONSE SPEED WITH LESS TEMPERATURE DEPENDENCE CANON KABUSHIKI KAISHA (JP) 1996-03-26 US disclosed
US-5409636-A Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KABUSHIKI KAISHA (JP) 1995-04-25 US disclosed
EP-0352480-B1 Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KK (JP) 1995-03-22 EP disclosed
EP-0347944-B1 Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KK (JP) 1995-02-01 EP disclosed
EP-0350937-B1 Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KK (JP) 1995-01-04 EP disclosed
US-5364559-A Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KABUSHIKI KAISHA (JP) 1994-11-15 US disclosed
EP-0347940-B1 Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KK (JP) 1994-09-21 EP disclosed
EP-0347943-B1 Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KK (JP) 1994-09-14 EP disclosed
EP-0355313-B1 Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KK (JP) 1994-08-31 EP disclosed
US-5183586-A For use in optical shutters having improved response to an el field CANON KABUSHIKI KAISHA (JP) 1993-02-02 US disclosed
EP-0255962-B1 OPTICALLY ACTIVE MESOMORPHIC COMPOUND CANON KABUSHIKI KAISHA (JP) 1993-01-27 EP disclosed
US-5143643-A Liquid crystals CANON KABUSHIKI KAISHA (JP) 1992-09-01 US disclosed
EP-0355313-A2 Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KABUSHIKI KAISHA (JP) 1990-02-28 EP disclosed
EP-0352480-A2 Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KABUSHIKI KAISHA (JP) 1990-01-31 EP disclosed
EP-0350937-A2 Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KABUSHIKI KAISHA (JP) 1990-01-17 EP disclosed
EP-0347943-A2 Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KABUSHIKI KAISHA (JP) 1989-12-27 EP disclosed
EP-0347940-A2 Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KABUSHIKI KAISHA (JP) 1989-12-27 EP disclosed
EP-0347944-A2 Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KABUSHIKI KAISHA (JP) 1989-12-27 EP disclosed
EP-0255962-A2 Optically active mesomorphic compound CANON KABUSHIKI KAISHA (JP) 1988-02-17 EP disclosed