SCHEMBL8944916

SCHEMBL8944916

CCCCCOC(C)CCCCCOS(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2C Q5R387 1/20 0.42
MCHR1 Q99705 1/20 0.40
CA9 Q16790 9/20 0.39
CA2 P00918 9/20 0.39
CA12 O43570 5/20 0.39
RECQL P46063 2/20 0.39
GLA P06280 1/20 0.39
HPGD P15428 1/20 0.39
TSHR P16473 1/20 0.39
MAPK1 P28482 1/20 0.39
EPHX2 P34913 1/20 0.39
BLM P54132 1/20 0.39
CA1 P00915 9/20 0.37
PSMD10 O75832 1/20 0.37
NR1I2 O75469 1/20 0.36
CA7 P43166 3/20 0.36
CA14 Q9ULX7 3/20 0.36
CA3 P07451 2/20 0.36
CA4 P22748 2/20 0.36
CA6 P23280 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9489603 0.97 PLA2G2C (0.42) PLA2G2CMCHR1CA9CA2CA12
SCHEMBL9489252 0.96 PLA2G2C (0.41) PLA2G2CMCHR1CA9CA2CA12
SCHEMBL9488585 0.92 PLA2G2C (0.41) PLA2G2CMCHR1CA9CA2CA12
SCHEMBL6130074 0.87 PLA2G2C (0.42) PLA2G2CMCHR1CA9CA2CA12
SCHEMBL9512608 0.87 PLA2G2C (0.44) PLA2G2CMCHR1CA9CA2CA12
SCHEMBL9723718 0.87 PLA2G2C (0.44) PLA2G2CMCHR1CA9CA2CA12
SCHEMBL9488453 0.87 PLA2G2C (0.44) PLA2G2CMCHR1CA9CA2CA12
SCHEMBL10725263 0.86 RECQL (0.50) PLA2G2CMCHR1CA9CA2CA12
SCHEMBL2194649 0.86 RECQL (0.50) PLA2G2CMCHR1CA9CA2CA12
SCHEMBL5015857 0.86 RECQL (0.50) PLA2G2CMCHR1CA9CA2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5501818-A PYRIMIDINE COMPOUNDS, IMPROVED RESPONSE SPEED WITH LESS TEMPERATURE DEPENDENCE CANON KABUSHIKI KAISHA (JP) 1996-03-26 US disclosed
EP-0347944-B1 Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KK (JP) 1995-02-01 EP disclosed
EP-0347940-B1 Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KK (JP) 1994-09-21 EP disclosed
US-5292453-A Fluorine containing chiral smectic liquid crystal CANON KABUSHIKI KAISHA (JP) 1994-03-08 US disclosed
EP-0255962-B1 OPTICALLY ACTIVE MESOMORPHIC COMPOUND CANON KABUSHIKI KAISHA (JP) 1993-01-27 EP disclosed
US-5143643-A Liquid crystals CANON KABUSHIKI KAISHA (JP) 1992-09-01 US disclosed
EP-0347940-A2 Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KABUSHIKI KAISHA (JP) 1989-12-27 EP disclosed
EP-0347944-A2 Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KABUSHIKI KAISHA (JP) 1989-12-27 EP disclosed
EP-0255962-A2 Optically active mesomorphic compound CANON KABUSHIKI KAISHA (JP) 1988-02-17 EP disclosed