Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 3/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.74 |
| ▸ | TP53 | P04637 | 2/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.74 |
| ▸ | MAPT | P10636 | 2/20 | 0.74 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.74 |
| ▸ | RECQL | P46063 | 2/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.74 |
| ▸ | HTR2C | P28335 | 4/20 | 0.72 |
| ▸ | IMPDH2 | P12268 | 5/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29729330 | 0.85 | MAPT (1.00) | HTR2BMEN1TP53CYP1A2CYP3A4 | |
| SCHEMBL173735 | 0.85 | MAPT (1.00) | HTR2BMEN1TP53CYP1A2CYP3A4 | |
| SCHEMBL29391435 | 0.85 | MAPT (1.00) | HTR2BMEN1TP53CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL31077673 | 0.84 | HTR2C (1.00) | HTR2BMEN1TP53CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL2116886 | 0.84 | HTR2C (1.00) | HTR2BMEN1TP53CYP1A2CYP3A4 | |
| SCHEMBL8944943 | 0.83 | HTR2B (0.75) | HTR2BMEN1TP53CYP1A2CYP3A4 | |
| SCHEMBL8945056 | 0.83 | MAPT (0.67) | HTR2BMEN1TP53CYP1A2CYP3A4 | |
| SCHEMBL8944987 | 0.83 | KDM4E (0.71) | HTR2BMEN1TP53CYP1A2CYP3A4 | |
| SCHEMBL8944894 | 0.81 | HTR2B (0.72) | HTR2BMEN1TP53CYP1A2CYP3A4 | |
| SCHEMBL12110170 | 0.78 | HTR2B (0.64) | HTR2BMEN1TP53CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5508288-A | Indole derivatives as 5HT1C antagonists | SMITHKLINE BEECHAM, P.L.C. (GB) | 1996-04-16 | — | — | US | disclosed |