Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 5/20 | 0.56 |
| ▸ | VKORC1 | Q9BQB6 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | PCSK7 | Q16549 | 1/20 | 0.51 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945550 | 0.85 | NQO1 (0.50) | NQO1VKORC1ALDH1A1MEN1ABCB11 | |
| SCHEMBL8945650 | 0.85 | CYP2C9 (0.50) | NQO1VKORC1ALDH1A1MEN1ABCB11 | |
| SCHEMBL9210173 | 0.81 | NQO1 (0.61) | NQO1VKORC1ALDH1A1MEN1ABCB11 | |
| SCHEMBL8945286 | 0.79 | NQO1 (0.59) | NQO1VKORC1ALDH1A1MEN1ABCB11 | |
| SCHEMBL7354775 | 0.77 | NQO1 (0.75) | NQO1VKORC1ALDH1A1MEN1ABCB11 | |
| SCHEMBL27687934 | 0.76 | NQO1 (0.57) | NQO1VKORC1ALDH1A1MEN1ABCB11 | |
| SCHEMBL8945492 | 0.75 | NQO1 (0.60) | NQO1VKORC1ALDH1A1MEN1LMNA | |
| SCHEMBL8945266 | 0.75 | NQO1 (0.61) | NQO1VKORC1ALDH1A1MEN1ABCB11 | |
| SCHEMBL8806732 | 0.75 | NQO1 (0.71) | NQO1VKORC1ALDH1A1MEN1ABCB11 | |
| SCHEMBL5072364 | 0.75 | NQO1 (0.71) | NQO1VKORC1ALDH1A1MEN1ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510375-A | VIRICIDES TREATING INFECTION CAUSED BY HUMAN IMMUNODEFICIENCY VIRUS AND AIDS | WARNER-LAMBERT COMPANY (US) | 1996-04-23 | — | — | US | disclosed |