Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | GLA | P06280 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | CASP1 | P29466 | 2/20 | 0.52 |
| ▸ | CASP7 | P55210 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 4/20 | 0.52 |
| ▸ | CA9 | Q16790 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29752815 | 0.96 | SRC (0.64) | SRCKDM4EALDH1A1HPGDGLA | |
| SCHEMBL72225 | 0.96 | SRC (0.64) | SRCKDM4EALDH1A1HPGDGLA | |
| SCHEMBL9177814 | 0.86 | SRC (0.53) | SRCKDM4EALDH1A1HPGDGLA | |
| SCHEMBL13840542 | 0.85 | SRC (0.64) | SRCKDM4EALDH1A1HPGDGLA | |
| SCHEMBL3994327 | 0.85 | SRC (0.64) | SRCKDM4EALDH1A1HPGDGLA | |
| SCHEMBL14947915 | 0.85 | SRC (0.60) | SRCKDM4EALDH1A1HPGDGLA | |
| SCHEMBL10349724 | 0.84 | SRC (0.62) | SRCKDM4EALDH1A1HPGDGLA | |
| Lysine SCHEMBL6426494 | 0.84 | SRC (0.51) | SRCKDM4EALDH1A1HPGDGLA | |
| SCHEMBL24807336 | 0.83 | SRC (0.64) | SRCKDM4EALDH1A1HPGDGLA | |
| SCHEMBL7576024 | 0.83 | KDM4E (0.74) | SRCKDM4EALDH1A1HPGDGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5580749-A | Internal reference for chemically modified spheres | GEORGIA TECH RESEARCH CORPORATION (US) | 1996-12-03 | — | — | US | disclosed |