Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | PCSK7 | Q16549 | 1/20 | 0.48 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | VKORC1 | Q9BQB6 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945552 | 0.83 | NQO1 (0.58) | NQO1ALDH1A1CYP2C9MEN1ABCB11 | |
| SCHEMBL7388201 | 0.82 | ABCG2 (0.43) | ALDH1A1CYP2C9LMNATP53CYP1A2 | |
| SCHEMBL8945251 | 0.79 | CYP2C9 (0.48) | NQO1ALDH1A1CYP2C9MEN1CYP3A4 | |
| SCHEMBL8945249 | 0.78 | NQO1 (0.47) | NQO1ALDH1A1CYP2C9MEN1ABCB11 | |
| SCHEMBL5072364 | 0.78 | NQO1 (0.71) | NQO1ALDH1A1CYP2C9MEN1ABCB11 | |
| SCHEMBL8806732 | 0.78 | NQO1 (0.71) | NQO1ALDH1A1CYP2C9MEN1ABCB11 | |
| SCHEMBL8806304 | 0.77 | NQO1 (0.69) | NQO1ALDH1A1CYP2C9MEN1ABCB11 | |
| SCHEMBL8934498 | 0.76 | NQO1 (0.58) | NQO1ALDH1A1CYP2C9MEN1ABCB11 | |
| SCHEMBL7354775 | 0.75 | NQO1 (0.75) | NQO1ALDH1A1CYP2C9MEN1ABCB11 | |
| SCHEMBL7378712 | 0.74 | ABCG2 (0.46) | ALDH1A1CYP2C9LMNATP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510375-A | VIRICIDES TREATING INFECTION CAUSED BY HUMAN IMMUNODEFICIENCY VIRUS AND AIDS | WARNER-LAMBERT COMPANY (US) | 1996-04-23 | — | — | US | disclosed |