SCHEMBL8945820

SCHEMBL8945820

Cc1nsc(S(C)(=O)=O)c1C#N

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.39
RECQL P46063 1/20 0.39
LMNA P02545 3/20 0.36
ALDH1A1 P00352 3/20 0.36
POLB P06746 2/20 0.36
RAB9A P51151 1/20 0.36
NPSR1 Q6W5P4 2/20 0.32
GRIA2 P42262 1/20 0.31
GRIA4 P48058 1/20 0.31
KDM4E B2RXH2 2/20 0.31
MAPT P10636 2/20 0.31
KMT2A Q03164 2/20 0.31
HPGD P15428 2/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
ALOX15 P16050 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5941009 0.79 GRIA2 (0.33) ALDH1A1POLBGRIA2GRIA4KDM4E
SCHEMBL6833252 0.77 RECQL (0.33) RECQLALDH1A1POLBNPSR1KDM4E
SCHEMBL8996614 0.72
SCHEMBL8478500 0.70
SCHEMBL14790120 0.67
SCHEMBL15159478 0.67
SCHEMBL164493 0.67
SCHEMBL7817973 0.65 HTT (0.42) HTTRECQLLMNAALDH1A1POLB
SCHEMBL7815343 0.64 GAA (0.44) HTTRECQLLMNAALDH1A1POLB
SCHEMBL20828414 0.64 HTT (0.53) HTTRECQLLMNAALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5578622-A FUNGICIDE OR BACTERICIDE FOR USE IN INDUSTRY, AGRICULTURE AND MEDICINE ASAMURA PATENT OFFICE (JP) 1996-11-26 US disclosed
EP-0697409-A1 Isothiazole derivatives containing (an) iodoalkylnyl group(s), their preparation and their use as fungicide and/or bactericide NIHON NOHYAKU CO., LTD. (JP) 1996-02-21 EP disclosed