SCHEMBL8947348

SCHEMBL8947348

CSc1ccc(C2C(O)[C@@]3(O)C(c4ccccc4)[C@@](O)([C@H](O)CO)[C@@]23O)cc1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 1/20 0.33
ABCB1 P08183 1/20 0.31
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL77133 0.89 ABCB1 (0.34) ABCB1
SCHEMBL1221056 0.87 ABCB1 (0.33) ABCB1
SCHEMBL812863 0.87 ABCB1 (0.33) ABCB1
SCHEMBL813668 0.85 KDM1A (0.32) ABCB1
SCHEMBL813409 0.85 KDM1A (0.32) ABCB1
SCHEMBL1221653 0.85 SLC5A2 (0.32) SLC5A2ABCB1
SCHEMBL9063456 0.85 SLC5A2 (0.33) SLC5A2ABCB1
SCHEMBL5931178 0.81
SCHEMBL5931052 0.81 ABCB1 (0.31) ABCB1
SCHEMBL121157 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210189085-A1 Polyolefin Polymers With Increased Melt Strength W. R. GRACE & CO.-CONN 2021-06-24 US disclosed
US-20190127552-A1 Polyolefin Polymers With Increased Melt Strength GRACE W R & CO (US) 2019-05-02 US disclosed
US-5574174-A 1,3-2,4-DI/SUBSTITUTED ARYLIDENE/-D-SORBITOLS, WHERE SUBSTITUTED ARYLIDENE MAY INCLUDE OPTIONALLY SUBSTITUTED THIOPHENYLIDENE MONTELL NORTH AMERICA INC. (US) 1996-11-12 US disclosed
US-5470898-A Sorbitol derivatives as nucleators and clarifiers for polyolefins, and polyolefin compositions obtained therewith MONTELL NORTH AMERICA INC. (US) 1995-11-28 US disclosed
EP-0632091-A2 Sorbitol derivatives as nucleators and clarifiers for polyolefins, and polyolefin compositions obtained therewith MONTELL NORTH AMERICA INC. (US) 1995-01-04 EP disclosed