Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 8/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.30 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8947700 | 0.93 | F2 (0.35) | F2KCNA5HPGDALDH1A1CYP3A4 | |
| Trifluoroacetic Acid SCHEMBL8947764 | 0.92 | F2 (0.33) | F2KCNA5 | |
| SCHEMBL7298314 | 0.90 | F2 (0.42) | F2KCNA5HPGD | |
| SCHEMBL8947624 | 0.89 | F2 (0.44) | F2ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL8948194 | 0.84 | F2 (0.46) | F2 | |
| SCHEMBL7394423 | 0.84 | BCHE (0.42) | F2 | |
| Hydrochloric Acid SCHEMBL7391915 | 0.83 | BCHE (0.42) | F2 | |
| Hydrochloric Acid SCHEMBL8947651 | 0.83 | F2 (0.44) | F2ALDH1A1 | |
| SCHEMBL8947742 | 0.82 | F2 (0.41) | F2ALDH1A1 | |
| SCHEMBL8947704 | 0.82 | F2 (0.43) | F2KCNA5HPGDALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578594-A | ANTICOAGULANTS | HOFFMANN-LA ROCHE INC. (US) | 1996-11-26 | — | — | US | disclosed |
| US-5405854-A | Anticoagulants | HOFFMANN-LA ROCHE INC. (US) | 1995-04-11 | — | — | US | disclosed |