SCHEMBL8948232

SCHEMBL8948232

CC(=O)C=CC1CCC(C)CC1

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.32
HDAC2 Q92769 1/20 0.31
PTPN2 P17706 1/20 0.30
PTPN1 P18031 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8948230 1.00 EPHX1 (0.32) EPHX1HDAC2PTPN2PTPN1
SCHEMBL319121 0.91
SCHEMBL319122 0.91
SCHEMBL2478199 0.82 TSHR (0.35) EPHX1HDAC2PTPN1
SCHEMBL31693836 0.82 EPHX2 (0.33) HDAC2PTPN2PTPN1
SCHEMBL6032582 0.82 TSHR (0.35) EPHX1HDAC2PTPN1
SCHEMBL10615509 0.81
SCHEMBL10615513 0.81
SCHEMBL31356724 0.81 PTPN2 (0.35) PTPN2PTPN1
SCHEMBL10973436 0.80 EPHX1 (0.35) EPHX1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5484949-A Method for the synthesis of α β-unsaturated ketones NIPPON SODA CO., LTD. (JP) 1996-01-16 US disclosed
EP-0454867-A1 A METHOD FOR THE SYNTHESIS OF -g(a), -g(b)-UNSATURATED KETONES. NIPPON SODA CO (JP) 1991-11-06 EP disclosed
WO-1991007370-A1 A METHOD FOR THE SYNTHESIS OF α, β-UNSATURATED KETONES NIPPON SODA CO., LTD. (JP) 1991-05-30 WO disclosed