SCHEMBL8948303

SCHEMBL8948303

CCCCCC1COC(c2ccc(-c3ccc(-c4ccc(CC)c(F)c4F)cc3)c(F)c2)OC1

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
RARB P10826 1/20 0.34
RORC P51449 2/20 0.31
RORA P35398 1/20 0.30
NR1H4 Q96RI1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8948472 0.99 RARB (0.36) RARBRORCRORANR1H4
SCHEMBL8948302 0.93 RARB (0.34) RARB
SCHEMBL8948309 0.93 RARB (0.34) RARB
SCHEMBL8948272 0.93 RARB (0.36) RARB
SCHEMBL8948240 0.93 CYP3A4 (0.30)
SCHEMBL8948332 0.92 RARB (0.38) RARB
SCHEMBL8948446 0.92 RARB (0.38) RARB
SCHEMBL8948449 0.92 RARB (0.35) RARB
SCHEMBL8948469 0.92 RARB (0.38) RARB
SCHEMBL8948485 0.92 RARB (0.38) RARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8187494-B2 Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2012-05-29 US disclosed