Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 2/20 | 0.40 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8948330 | 0.86 | HDAC3 (0.42) | TDP1CNR2TSHRKDM4ECYP2C9 | |
| SCHEMBL8590724 | 0.85 | MEN1 (0.46) | TDP1GRIK1CNR2TSHRANPEP | |
| SCHEMBL8950931 | 0.83 | CYP1A2 (0.50) | — | |
| SCHEMBL10482476 | 0.78 | AOC3 (0.47) | GRIK1CNR2TSHRANPEPERAP1 | |
| SCHEMBL2987292 | 0.78 | ERAP1 (0.53) | ANPEPERAP1MMEERAP2MEN1 | |
| SCHEMBL2987289 | 0.78 | ERAP1 (0.53) | ANPEPERAP1MMEERAP2MEN1 | |
| SCHEMBL23064151 | 0.77 | TSHR (0.49) | GRIK1CNR2TSHRMEN1KMT2A | |
| SCHEMBL3663595 | 0.77 | PPARG (0.46) | TDP1GRIK1CNR2TSHRANPEP | |
| SCHEMBL23064152 | 0.77 | TSHR (0.49) | GRIK1CNR2TSHRMEN1KMT2A | |
| SCHEMBL7402281 | 0.77 | MEN1 (0.44) | TDP1GRIK1CNR2TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514808-A | Hydroxyl ions as unique therapeutic agents and compounds that modulate these ions | FHJ SCIENTIFIC, INC (US) | 1996-05-07 | — | — | US | claimed |