Known targets — ChEMBL curated mechanism
823298382338688239847Rdl1Rdl2Rdl3
The experimentally established mechanism targets of Lindane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 6/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | HTR1D | P28221 | 2/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8755471 | 0.92 | HTR1B (0.50) | HTR1BCYP2C9CYP1A2CYP2C19MEN1 | |
| SCHEMBL27782966 | 0.90 | MEN1 (0.51) | HTR1BCYP2C9CYP1A2CYP2C19MEN1 | |
| SCHEMBL7054033 | 0.90 | MEN1 (0.51) | HTR1BCYP2C9CYP1A2CYP2C19MEN1 | |
| SCHEMBL28897589 | 0.90 | MEN1 (0.51) | HTR1BCYP2C9CYP1A2CYP2C19MEN1 | |
| SCHEMBL20678465 | 0.90 | MEN1 (0.51) | HTR1BCYP2C9CYP1A2CYP2C19MEN1 | |
| Water SCHEMBL28168267 | 0.89 | MEN1 (0.50) | HTR1BCYP2C9CYP1A2CYP2C19MEN1 | |
| SCHEMBL27804518 | 0.87 | CYP1A2 (0.56) | HTR1BCYP2C9CYP1A2CYP2C19CNR1 | |
| SCHEMBL28096308 | 0.81 | MEN1 (0.47) | HTR1BCYP2C9CYP1A2CYP2C19MEN1 | |
| SCHEMBL7753974 | 0.80 | CYP2C9 (0.46) | HTR1BCYP2C9CYP1A2CYP2C19MEN1 | |
| SCHEMBL6742971 | 0.79 | CYP2C9 (0.45) | HTR1BCYP2C9CYP1A2CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8236166-A | — | — | None | — | — | JP | disclosed |
| JP-H08236166-A | CHARGE TRANSPORT MEDIUM, AND ELECTROCHEMICAL BATTERY CONTAINING THE SAME | BASF AG | 1996-09-13 | — | — | JP | disclosed |