Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL91637 | 0.78 | CES1 (0.40) | PSMB5PARP1 | |
| SCHEMBL11189590 | 0.74 | CES1 (0.36) | PSMB5PARP1 | |
| SCHEMBL8948723 | 0.71 | MAPK1 (0.35) | TDP1 | |
| SCHEMBL2480784 | 0.70 | MAOB (0.32) | ADORA2AMAPTGAA | |
| SCHEMBL30954241 | 0.70 | PSMB5 (0.33) | PSMB5PARP1 | |
| SCHEMBL86812 | 0.68 | PDE7A (0.40) | MAPTLMNAMEN1NPC1ALDH1A1 | |
| SCHEMBL8948529 | 0.67 | ADORA2A (0.38) | ADORA2AMAPTTHRBMEN1NPC1 | |
| SCHEMBL21603443 | 0.66 | CYP3A4 (0.35) | MAPTLMNAALDH1A1TDP1 | |
| SCHEMBL8948579 | 0.66 | ADORA2A (0.40) | ADORA2AMAPTTHRBMEN1NPC1 | |
| SCHEMBL17843994 | 0.66 | GAA (0.44) | ADORA2AMAPTALDH1A1PARP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521147-A | HERBICIDES | FMC CORPORATION (US) | 1996-05-28 | — | — | US | disclosed |
| WO-1995005079-A1 | 3-(BENZOFURAN-7-YL)-6-HALOALKYLURACILS | FMC CORPORATION (US) | 1995-02-23 | — | — | WO | disclosed |