Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL895817 | 0.92 | KCNH2 (0.47) | KCNH2CYP3A4CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL895467 | 0.92 | KCNH2 (0.47) | KCNH2CYP3A4CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL896091 | 0.92 | KCNH2 (0.49) | KCNH2CYP3A4CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL895666 | 0.92 | KCNH2 (0.49) | KCNH2CYP3A4CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL475246 | 0.92 | KCNH2 (0.47) | KCNH2CYP3A4CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL896141 | 0.91 | KCNH2 (0.46) | KCNH2CYP3A4CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL20952269 | 0.91 | KCNH2 (0.46) | KCNH2CYP3A4CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL895411 | 0.91 | KCNH2 (0.46) | KCNH2CYP3A4CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL895086 | 0.91 | KCNH2 (0.47) | KCNH2CYP3A4CYP2C9CYP1A2 | |
| SCHEMBL896045 | 0.90 | KCNH2 (0.46) | KCNH2CYP3A4CYP2C9CYP2C19CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120083483-A1 | INHIBITORS OF HEPATITIS C VIRUS REPLICATION | MERCK SHARP & DOHME CORP (NJ) | 2012-04-05 | — | — | US | claimed |
| US-20120083483-A1 | INHIBITORS OF HEPATITIS C VIRUS REPLICATION | MERCK SHARP & DOHME CORP (NJ) | 2012-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120083483-A1 | INHIBITORS OF HEPATITIS C VIRUS REPLICATION | HAVCR2, HCCS, EIF2AK2 | KCNH2 4621/4885CYP3A4 1646/4885CYP2C9 2551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.