SCHEMBL894918

SCHEMBL894918

N#CC1CC(F)CN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1335470 1.00
SCHEMBL13070113 1.00
Hydrochloric Acid SCHEMBL1153672 0.98
Bromide SCHEMBL27682610 0.98
SCHEMBL27558850 0.84 CTSC (0.39)
SCHEMBL1337026 0.75
SCHEMBL1676738 0.75
SCHEMBL1676884 0.75
SCHEMBL3159738 0.74
SCHEMBL14972886 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4055014-B1 PYRROLIDINE AND PIPERIDINE COMPOUNDS YUHAN CORP (KR) 2025-04-30 EP claimed
EP-2776442-A1 [1, 2, 3]TRIAZOLO [4, 5 -D]PYRIMIDINE DERIVATIVES AS AGONISTS OF THE CANNABINOID RECEPTOR 2 F.HOFFMANN-LA ROCHE AG (CH) 2014-09-17 EP claimed
WO-2013068306-A1 [1, 2, 3] TRIAZOLO [4, 5 -D] PYRIMIDINE DERIVATIVES AS AGONISTS OF THE CANNABINOID RECEPTOR 2 F. HOFFMANN-LA ROCHE AG (CH) 2013-05-16 WO claimed
CN-101087757-B Novel dipeptidyl peptidase iv inhibitors, process for their preparation and compositions containing them GLENMARK PHARMACEUTICALS SA 2013-01-02 CN claimed
EP-1931633-A2 DERIVATIVES OF 3-AZABICYCLO[3.1.0]HEXANE AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS Ranbaxy Laboratories Limited (IN) 2008-06-18 EP claimed
CN-101087757-A Novel dipeptidyl peptidase iv inhibitors, process for their preparation and compositions containing them GLENMARK PHARMACEUTICALS SA (CH) 2007-12-12 CN claimed
US-7268150-B2 2-cyano-4-fluoropyrrolidine derivative or its salt YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 2007-09-11 US claimed
WO-2007099385-A1 DIPEPTIDYL PEPTIDASE IV INHIBITOR COMPOUNDS AND COMPOSITIONS GLENMARK PHARMACEUTICALS S.A. (US) 2007-09-07 WO claimed
EP-1799639-A1 NOVEL DIPEPTIDYL PEPTIDASE IV INHIBITORS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION Glenmark Pharmaceuticals S.A. (CH) 2007-06-27 EP claimed
CN-1312127-C 2-cyano-4-fluoropyrrolidine derivative or its salt YAMANOUCHI PHARMA CO LTD (JP) 2007-04-25 CN claimed
WO-2007029086-A2 DERIVATIVES OF 3-AZABICYCLO[3.1.0]HEXANE AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS RANBAXY LABORATORIES LIMITED (IN) 2007-03-15 WO claimed
WO-2006040625-A1 NOVEL DIPEPTIDYL PEPTIDASE IV INHIBITORS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION GLENMARK PHARMACEUTICALS S.A. (US) 2006-04-20 WO claimed
CN-1665785-A 2-cyano-4-fluoropyrrolidine derivative or its salt YAMANOUCHI PHARMA CO LTD (JP) 2005-09-07 CN claimed
US-20050176771-A1 2-Cyano-4-fluoropyrrolidine derivative or its salt ASTELLAS PHARMA INC. (JP) 2005-08-11 US claimed
EP-1541551-A1 2-CYANO-4-FLUOROPYRROLIDINE DERIVATIVE OR ITS SALT YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 2005-06-15 EP claimed
CN-114867719-B Pyrrolidine and piperidine compounds 柳韩洋行 2024-06-25 CN disclosed
CN-117957228-A SGC stimulators 帝善多制药公司 2024-04-30 CN disclosed
US-20050176771-A1 2-Cyano-4-fluoropyrrolidine derivative or its salt ASTELLAS PHARMA INC. (JP) 2005-08-11 US disclosed
EP-1541551-A1 2-CYANO-4-FLUOROPYRROLIDINE DERIVATIVE OR ITS SALT YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 2005-06-15 EP disclosed
EP-1535907-A1 BENZENESULFONATE OF 4-FLUORO-2-CYANOPYRROLIDINE DERIVATIVE TAISHO PHARMACEUTICAL CO., LTD (JP) 2005-06-01 EP disclosed