SCHEMBL8949600

SCHEMBL8949600

C[C@@H](O)[C@H]1O[C@H](OCC[Si](C)(C)C)[C@H](OCc2ccccc2)[C@@H](OCc2ccccc2)[C@H]1OCc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 6/20 0.42
CDC25B P30305 6/20 0.42
SSTR1 P30872 1/20 0.39
SSTR2 P30874 1/20 0.39
SSTR4 P31391 1/20 0.39
SSTR3 P32745 1/20 0.39
SSTR5 P35346 1/20 0.39
BCHE P06276 4/20 0.38
PDPK1 O15530 1/20 0.38
MTOR P42345 1/20 0.38
PTPN2 P17706 2/20 0.37
PTPN6 P29350 2/20 0.37
PTPN11 Q06124 2/20 0.37
HTT P42858 2/20 0.36
TACR1 P25103 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8949507 1.00 PTPN1 (0.42) PTPN1CDC25BSSTR1SSTR2SSTR4
SCHEMBL4283122 0.90 PTPN1 (0.46) PTPN1CDC25BSSTR1SSTR2SSTR4
SCHEMBL16027346 0.90 PTPN1 (0.46) PTPN1CDC25BSSTR1SSTR2SSTR4
SCHEMBL16027437 0.90 PTPN1 (0.46) PTPN1CDC25BSSTR1SSTR2SSTR4
SCHEMBL4285024 0.90 PTPN1 (0.46) PTPN1CDC25BSSTR1SSTR2SSTR4
SCHEMBL16027439 0.90 PTPN1 (0.46) PTPN1CDC25BSSTR1SSTR2SSTR4
SCHEMBL16027344 0.90 PTPN1 (0.46) PTPN1CDC25BSSTR1SSTR2SSTR4
SCHEMBL20056306 0.90 PTPN1 (0.46) PTPN1CDC25BSSTR1SSTR2SSTR4
SCHEMBL8949781 0.81 BCHE (0.36) PTPN1CDC25BSSTR1SSTR2SSTR4
SCHEMBL8949775 0.81 BCHE (0.36) PTPN1CDC25BSSTR1SSTR2SSTR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5512470-A Method for inhibiting sialidase activity E. I. DU PONT DE NEMOURS AND COMPANY (US) 1996-04-30 US disclosed
US-5489675-A POWERFUL ANTIVIRAL AND ANTIBACTERIAL AGENTS SPECIALLY INFLUENZA VIRUS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1996-02-06 US disclosed