Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | FDPS | P14324 | 4/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7924458 | 0.98 | CA1 (0.50) | CA1FFAR4FFAR1OPRM1FDPS | |
| SCHEMBL11202132 | 0.98 | CA1 (0.50) | CA1FFAR4FFAR1OPRM1FDPS | |
| SCHEMBL11492630 | 0.98 | CA1 (0.50) | CA1FFAR4FFAR1OPRM1FDPS | |
| SCHEMBL7186285 | 0.98 | CA1 (0.50) | CA1FFAR4FFAR1OPRM1FDPS | |
| SCHEMBL9692947 | 0.98 | CA1 (0.50) | CA1FFAR4FFAR1OPRM1FDPS | |
| SCHEMBL7278088 | 0.98 | CA1 (0.50) | CA1FFAR4FFAR1OPRM1FDPS | |
| SCHEMBL11827001 | 0.98 | CA1 (0.50) | CA1FFAR4FFAR1OPRM1FDPS | |
| SCHEMBL5489710 | 0.93 | CA1 (0.50) | CA1FFAR4FFAR1OPRM1FDPS | |
| SCHEMBL5484425 | 0.93 | CA1 (0.50) | CA1FFAR4FFAR1OPRM1FDPS | |
| SCHEMBL2529410 | 0.91 | FFAR4 (0.46) | CA1FFAR4FFAR1FDPSACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552441-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS AND RESPIRATORY SYSTEM DISORDERS | ELI LILLY AND COMPANY (US) | 1996-09-03 | — | — | US | disclosed |
| EP-0686151-A1 | SUBSTITUTED CYCLIC CARBONYLS AND DERIVATIVES THEREOF USEFUL AS RETROVIRAL PROTEASE INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-12-13 | — | — | EP | disclosed |
| US-5324743-A | Leukotriene B4 antagonists | ELI LILLY AND COMPANY (US) | 1994-06-28 | — | — | US | disclosed |
| US-4338315-A | RHINOVIRUSES | ELI LILLY AND COMPANY (US) | 1982-07-06 | — | — | US | disclosed |