Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD81 | P60033 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8950422 | 1.00 | CD81 (0.37) | CD81CYP1A2CYP2D6MAPTCYP2C9 | |
| SCHEMBL5362246 | 0.84 | MAPT (0.47) | CD81CYP1A2CYP2D6MAPTCYP2C9 | |
| SCHEMBL23749600 | 0.81 | KDM4E (0.30) | KDM4EALDH1A1HPGD | |
| SCHEMBL234427 | 0.78 | MEN1 (0.38) | CD81ALDH1A1PPARGBACE1 | |
| SCHEMBL2049619 | 0.78 | MEN1 (0.38) | CD81ALDH1A1PPARGBACE1 | |
| SCHEMBL1765494 | 0.78 | CD81 (0.44) | CD81CYP2C9KDM4EPPARGBACE1 | |
| SCHEMBL129059 | 0.78 | CD81 (0.44) | CD81CYP2C9KDM4EPPARGBACE1 | |
| SCHEMBL2147310 | 0.77 | — | — | |
| SCHEMBL699232 | 0.77 | — | — | |
| SCHEMBL7279044 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012065065-A9 | METHODS AND COMPOSITIONS FOR MODULATING HAIR GROWTH, WOUND HEALING AND SCAR REVISION | FOLLICA, INC. (US) | 2012-10-11 | — | — | WO | disclosed |
| US-5502073-A | INSECTICIDES OR ANTHELMINTICS | THE WELLCOME FOUNDATION (GB) | 1996-03-26 | — | — | US | disclosed |
| EP-0294229-B1 | NOVEL HETEROCYCLIC PESTICIDAL COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-12-02 | — | — | EP | disclosed |
| EP-0294229-A2 | Novel heterocyclic pesticidal compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1988-12-07 | — | — | EP | disclosed |