Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.80 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | GRM8 | O00222 | 1/20 | 0.59 |
| ▸ | GRM6 | O15303 | 1/20 | 0.59 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.59 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.59 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.59 |
| ▸ | GRM5 | P41594 | 1/20 | 0.59 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.59 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.59 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.59 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.59 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.59 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.59 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.59 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.59 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.59 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.59 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.59 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL8950852 | 1.00 | GSR (0.80) | GSRCYP1A2GRM8GRM6GRIN2D | |
| Lysine SCHEMBL28521842 | 0.96 | GSR (0.80) | GSRCYP1A2GRM8GRM6GRIN2D | |
| Lysine SCHEMBL1065050 | 0.96 | GSR (0.80) | GSRCYP1A2GRM8GRM6GRIN2D | |
| Lysine SCHEMBL27928148 | 0.96 | GSR (0.80) | GSRCYP1A2GRM8GRM6GRIN2D | |
| Lysine SCHEMBL8759022 | 0.96 | GSR (0.80) | GSRCYP1A2GRM8GRM6GRIN2D | |
| Lysine SCHEMBL1065049 | 0.96 | GSR (0.80) | GSRCYP1A2GRM8GRM6GRIN2D | |
| (S)-2-Aminoadipic Acid SCHEMBL15845186 | 0.96 | GSR (0.80) | GSRCYP1A2GRM8GRM6GRIN2D | |
| Lysine SCHEMBL6275911 | 0.96 | GSR (0.80) | GSRCYP1A2GRM8GRM6GRIN2D | |
| Lysine SCHEMBL20677819 | 0.96 | GSR (0.80) | GSRCYP1A2GRM8GRM6GRIN2D | |
| (S)-2-Aminoadipic Acid SCHEMBL15845185 | 0.96 | GSR (0.80) | GSRCYP1A2GRM8GRM6GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10202333-B2 | Aqueous solution containing bis(N epsilon lauroyllysine)dicarboxylic acid diamide and/or salt thereof, and method for producing same | AJINOMOTO CO., INC. (JP) | 2019-02-12 | — | — | US | disclosed |
| US-20170260127-A1 | AQUEOUS SOLUTION CONTAINING BIS(N EPSILON LAUROYLLYSINE)DICARBOXYLIC ACID DIAMIDE AND/OR SALT THEREOF, AND METHOD FOR PRODUCING SAME | AJINOMOTO CO., INC. (JP) | 2017-09-14 | — | — | US | disclosed |
| EP-3205641-A1 | AQUEOUS SOLUTION CONTAINING BIS(N -LAUROYLLYSINE)DICARBOXYLIC ACID DIAMIDE AND/OR SALT THEREOF, AND METHOD FOR PRODUCING SAME | AJINOMOTO CO., INC. (JP) | 2017-08-16 | — | — | EP | disclosed |
| US-5491212-A | Method for preparing polysuccinimides using a rotary tray dryer | ROHM AND HAAS COMPANY (US) | 1996-02-13 | — | — | US | disclosed |