Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | XBP1 | P17861 | 1/20 | 0.55 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9167753 | 0.85 | MAPT (0.59) | MAPTKMT2AMEN1HTTRAB9A | |
| SCHEMBL8950786 | 0.85 | MAPT (0.59) | MAPTKMT2AMEN1HTTRAB9A | |
| SCHEMBL8950918 | 0.81 | MAPT (0.62) | MAPTKMT2AMEN1HTTRAB9A | |
| SCHEMBL20560345 | 0.79 | MAPT (0.68) | MAPTKMT2AMEN1HTTRAB9A | |
| SCHEMBL5597699 | 0.79 | KMT2A (0.90) | MAPTKMT2AMEN1HTTRAB9A | |
| SCHEMBL30101230 | 0.79 | KMT2A (0.90) | MAPTKMT2AMEN1HTTRAB9A | |
| SCHEMBL8950776 | 0.78 | MEN1 (0.62) | MAPTKMT2AMEN1HTTRAB9A | |
| SCHEMBL2096021 | 0.77 | MAPT (0.70) | MAPTKMT2AMEN1HTTRAB9A | |
| SCHEMBL2096025 | 0.77 | MAPT (0.75) | MAPTKMT2AMEN1HTTRAB9A | |
| SCHEMBL4548162 | 0.77 | KMT2A (0.87) | MAPTKMT2AMEN1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649835-A1 | Halopropiolamide compound, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-04-26 | — | — | EP | claimed |
| US-5538998-A | PEST CONTROL AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-07-23 | — | — | US | disclosed |
| EP-0649835-A1 | Halopropiolamide compound, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-04-26 | — | — | EP | disclosed |