Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8952592 | 1.00 | DAO (0.32) | DAOEPHX2ALDH1A1CYP2C19 | |
| SCHEMBL8952582 | 1.00 | DAO (0.32) | DAOEPHX2ALDH1A1CYP2C19 | |
| SCHEMBL8952606 | 1.00 | DAO (0.32) | DAOEPHX2ALDH1A1CYP2C19 | |
| SCHEMBL8952704 | 1.00 | DAO (0.32) | DAOEPHX2ALDH1A1CYP2C19 | |
| SCHEMBL8952577 | 1.00 | DAO (0.32) | DAOEPHX2ALDH1A1CYP2C19 | |
| SCHEMBL8952575 | 1.00 | DAO (0.32) | DAOEPHX2ALDH1A1CYP2C19 | |
| SCHEMBL5087490 | 0.99 | DAO (0.33) | DAOEPHX2 | |
| SCHEMBL6474547 | 0.99 | DAO (0.33) | DAOEPHX2 | |
| SCHEMBL4444532 | 0.99 | DAO (0.33) | DAOEPHX2 | |
| SCHEMBL8952566 | 0.88 | MAPK10 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0669825-A4 | HYDROXYL-CONTAINING COMPOUNDS. | CELL THERAPEUTICS INC (US) | 1996-04-03 | — | — | EP | disclosed |
| EP-0669825-A1 | HYDROXYL-CONTAINING COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1995-09-06 | — | — | EP | disclosed |
| WO-1994011001-A1 | HYDROXYL-CONTAINING COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1994-05-26 | — | — | WO | disclosed |