Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 3/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8952897 | 1.00 | CTSA (0.33) | CTSAFFAR1HMGCR | |
| SCHEMBL8953298 | 0.92 | KDM4E (0.35) | HMGCR | |
| SCHEMBL8953292 | 0.92 | KDM4E (0.35) | HMGCR | |
| SCHEMBL8952996 | 0.89 | CTSA (0.30) | CTSA | |
| SCHEMBL8952992 | 0.89 | CTSA (0.30) | CTSA | |
| SCHEMBL8953071 | 0.88 | — | — | |
| SCHEMBL8953061 | 0.88 | — | — | |
| SCHEMBL8952783 | 0.88 | — | — | |
| SCHEMBL8952788 | 0.88 | — | — | |
| SCHEMBL8952800 | 0.86 | HMGCR (0.40) | CTSAHMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506219-A | ANTICHOLESTEROL AND ANTILIPEMIC AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1996-04-09 | — | — | US | disclosed |