Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 11/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | HMGCR | P04035 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8952906 | 1.00 | GCGR (0.44) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL8952824 | 0.92 | ESR1 (0.42) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL8952827 | 0.92 | ESR1 (0.42) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL8952825 | 0.83 | HMGCR (0.48) | ESR1HMGCRCHRM1TBXA2RPDE4A | |
| SCHEMBL8952819 | 0.83 | HMGCR (0.48) | ESR1HMGCRCHRM1TBXA2RPDE4A | |
| SCHEMBL8876752 | 0.83 | GCGR (0.42) | GCGR | |
| SCHEMBL8952759 | 0.82 | ESR1 (0.39) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL8953109 | 0.82 | HMGCR (0.50) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL8953113 | 0.82 | HMGCR (0.50) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL8952763 | 0.82 | ESR1 (0.39) | GCGRESR1HMGCRCHRM1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506219-A | ANTICHOLESTEROL AND ANTILIPEMIC AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1996-04-09 | — | — | US | disclosed |
| EP-0444533-A2 | Quinoline and pyridine anchors for HMG-CoA reductase inhibitors | E.R. SQUIBB & SONS, INC. (US) | 1991-09-04 | — | — | EP | disclosed |