Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 2/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8952913 | 1.00 | HMGCR (0.51) | HMGCRESR1CHRM1TBXA2RPDE4A | |
| SCHEMBL8952900 | 1.00 | HMGCR (0.51) | HMGCRESR1CHRM1TBXA2RPDE4A | |
| SCHEMBL8953236 | 0.90 | HMGCR (0.51) | HMGCRESR1CHRM1TBXA2RPDE4A | |
| SCHEMBL8953264 | 0.90 | HMGCR (0.51) | HMGCRESR1CHRM1TBXA2RPDE4A | |
| SCHEMBL8952765 | 0.87 | HMGCR (0.51) | HMGCR | |
| SCHEMBL8952966 | 0.87 | HMGCR (0.51) | HMGCR | |
| SCHEMBL8952955 | 0.87 | HMGCR (0.51) | HMGCR | |
| SCHEMBL8953262 | 0.80 | — | — | |
| SCHEMBL8953252 | 0.80 | — | — | |
| SCHEMBL8953255 | 0.79 | HMGCR (0.49) | HMGCRESR1CHRM1TBXA2RPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506219-A | ANTICHOLESTEROL AND ANTILIPEMIC AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1996-04-09 | — | — | US | disclosed |