Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HMGCR | P04035 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8952985 | 1.00 | NPSR1 (0.35) | NPSR1KDM4EHTTL3MBTL1HMGCR | |
| SCHEMBL8953288 | 0.97 | HMGCR (0.37) | NPSR1KDM4EHTTL3MBTL1HMGCR | |
| SCHEMBL8953292 | 0.92 | KDM4E (0.35) | NPSR1KDM4EHMGCRALDH1A1HPGD | |
| SCHEMBL8953298 | 0.92 | KDM4E (0.35) | NPSR1KDM4EHMGCRALDH1A1HPGD | |
| SCHEMBL8952783 | 0.90 | — | — | |
| SCHEMBL8953010 | 0.90 | — | — | |
| SCHEMBL8953005 | 0.90 | — | — | |
| SCHEMBL8952788 | 0.90 | — | — | |
| SCHEMBL8953071 | 0.89 | — | — | |
| SCHEMBL8953061 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506219-A | ANTICHOLESTEROL AND ANTILIPEMIC AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1996-04-09 | — | — | US | disclosed |