Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8953067 | 1.00 | HMGCR (0.42) | HMGCRCTSA | |
| SCHEMBL8953077 | 0.90 | HMGCR (0.50) | HMGCR | |
| SCHEMBL8952739 | 0.90 | HMGCR (0.50) | HMGCR | |
| SCHEMBL8952944 | 0.89 | HMGCR (0.42) | HMGCR | |
| SCHEMBL8952977 | 0.85 | HMGCR (0.45) | HMGCR | |
| SCHEMBL8952706 | 0.82 | — | — | |
| SCHEMBL8952711 | 0.82 | — | — | |
| SCHEMBL8953165 | 0.81 | — | — | |
| SCHEMBL8953141 | 0.81 | — | — | |
| SCHEMBL8953159 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506219-A | ANTICHOLESTEROL AND ANTILIPEMIC AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1996-04-09 | — | — | US | disclosed |
| EP-0444533-A2 | Quinoline and pyridine anchors for HMG-CoA reductase inhibitors | E.R. SQUIBB & SONS, INC. (US) | 1991-09-04 | — | — | EP | disclosed |