Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8953363 | 1.00 | NR1I2 (0.44) | NR1I2NR4A2PDE4D | |
| SCHEMBL8953367 | 0.83 | NR1I2 (0.44) | NR1I2NR4A2PDE4D | |
| SCHEMBL8952934 | 0.82 | — | — | |
| SCHEMBL8952923 | 0.82 | — | — | |
| SCHEMBL8952817 | 0.82 | NR1I2 (0.53) | NR1I2NR4A2PDE4D | |
| SCHEMBL8952812 | 0.82 | NR1I2 (0.53) | NR1I2NR4A2PDE4D | |
| SCHEMBL8952803 | 0.82 | NR1I2 (0.53) | NR1I2NR4A2PDE4D | |
| SCHEMBL8952869 | 0.79 | NR1I2 (0.42) | NR1I2NR4A2PDE4D | |
| SCHEMBL8952873 | 0.79 | NR1I2 (0.51) | NR1I2NR4A2PDE4D | |
| SCHEMBL8953267 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506219-A | ANTICHOLESTEROL AND ANTILIPEMIC AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1996-04-09 | — | — | US | disclosed |
| EP-0444533-A2 | Quinoline and pyridine anchors for HMG-CoA reductase inhibitors | E.R. SQUIBB & SONS, INC. (US) | 1991-09-04 | — | — | EP | disclosed |