Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | KDM6B | O15054 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28019828 | 1.00 | TAAR1 (0.58) | TAAR1CYP1A2CTBP2MEN1KMT2A | |
| SCHEMBL7511969 | 1.00 | TAAR1 (0.58) | TAAR1CYP1A2CTBP2MEN1KMT2A | |
| SCHEMBL1368547 | 1.00 | TAAR1 (0.58) | TAAR1CYP1A2CTBP2MEN1KMT2A | |
| SCHEMBL28020294 | 0.86 | TAAR1 (0.57) | TAAR1MEN1KMT2AHIF1AALDH1A1 | |
| SCHEMBL4594693 | 0.86 | TAAR1 (0.57) | TAAR1MEN1KMT2AHIF1AALDH1A1 | |
| SCHEMBL8953540 | 0.84 | PPARA (0.50) | TAAR1CYP1A2CTBP2MEN1KMT2A | |
| SCHEMBL12191887 | 0.84 | TAAR1 (0.63) | TAAR1CYP1A2CTBP2MEN1KMT2A | |
| SCHEMBL27836008 | 0.84 | PPARG (0.59) | KDM6BPPARA | |
| SCHEMBL12191881 | 0.84 | TAAR1 (0.63) | TAAR1CYP1A2CTBP2MEN1KMT2A | |
| SCHEMBL5740450 | 0.84 | TAAR1 (0.63) | TAAR1CYP1A2CTBP2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514773-A | PARASITICIDES, ANTHELMINTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-07 | — | — | US | disclosed |