SCHEMBL8953877

SCHEMBL8953877

CC(C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)CN)C(C)C)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ C5AR1 P21730 2/20 0.55
▸ REN P00797 10/20 0.51
▸ APLNR P35414 1/20 0.50
▸ F2 P00734 1/20 0.49
▸ AGTR1 P30556 1/20 0.48
▸ AGTR2 P50052 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10622567 0.99 C5AR1 (0.54) C5AR1RENAPLNRF2AGTR1
SCHEMBL8953840 0.94 C5AR1 (0.52) C5AR1RENAPLNRF2
SCHEMBL8953791 0.92 C5AR1 (0.52) C5AR1RENAPLNRF2
SCHEMBL30002373 0.89 ACE (0.53) C5AR1APLNRF2
SCHEMBL5969903 0.88 ACE (0.53) C5AR1APLNRF2
SCHEMBL9181890 0.88 C5AR1 (0.50) C5AR1RENAPLNRF2
SCHEMBL9747695 0.87 SLC15A2 (0.46) C5AR1F2
SCHEMBL6382012 0.87 SLC15A2 (0.46) C5AR1F2
SCHEMBL9389399 0.87 SLC15A2 (0.46) C5AR1F2
SCHEMBL5969907 0.87 F2 (0.52) C5AR1RENAPLNRF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5550183-A Metal-peptide compositions and methods for stimulating hair growth PROCYTE CORPORATION (US) 1996-08-27 — — US disclosed
US-5348943-A Copper complexes with derivatives of glycyl-histidyl-lysine PROCYTE CORPORATION (US) 1994-09-20 — — US disclosed
EP-0314755-B1 Use of derivatives of GHL-Cu for the manufacture of a medicament for stimulating hair growth PROCYTE CORP (US) 1994-08-24 — — EP disclosed
US-5214032-A GHL-CU pharmaceutical compositions and compounds PROCYTE CORPORATION (US) 1993-05-25 — — US disclosed
US-5177061-A Method for stimulating hair growth using GHL-Cu complexes PROCYTE CORPORATION (US) 1993-01-05 — — US disclosed
EP-0500745-A1 METAL-PEPTIDE COMPOSITIONS AND COSMETIC METHODS FOR STIMULATING HAIR GROWTH PROCYTE CORPORATION (US) 1992-09-02 — — EP disclosed
US-5135913-A Increasing subcutaneous fat by administering copper-peptide complex PROCYTE CORPORATION (US) 1992-08-04 — — US disclosed
EP-0313643-B1 METHODS AND COMPOSITIONS FOR PREVENTING ULCERS PROCYTE CORPORATION (US) 1992-07-29 — — EP disclosed
US-5120831-A Hair growth stimulants PROCYTE CORPORATION (US) 1992-06-09 — — US disclosed
WO-1991007431-A1 METAL-PEPTIDE COMPOSITIONS AND METHODS FOR STIMULATING HAIR GROWTH PROCYTE CORPORATION (US) 1991-05-30 — — WO disclosed
WO-1988008851-A1 METHOD FOR INDUCING BIOLOGICAL COVERINGS IN WOUNDS PROCYTE CORPORATION (US) 1988-11-17 — — WO disclosed
WO-1988008695-A1 METHODS FOR STIMULATING HAIR GROWTH PROCYTE CORPORATION (US) 1988-11-17 — — WO disclosed
US-4767753-A GLYCYL-HISTIDYL-LYSINE DERIVATIVES PROCYTE CORPORATION (US) 1988-08-30 — — US disclosed
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