⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8954358 | 0.90 | — | — | |
| SCHEMBL7277636 | 0.85 | — | — | |
| SCHEMBL9472975 | 0.81 | — | — | |
| SCHEMBL7676927 | 0.81 | — | — | |
| SCHEMBL8954129 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL9473508 | 0.81 | — | — | |
| SCHEMBL8954232 | 0.81 | — | — | |
| SCHEMBL9474680 | 0.80 | — | — | |
| SCHEMBL7269753 | 0.79 | — | — | |
| SCHEMBL9264327 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5530017-A | CONGESTIVE HEART FAILURE, RENAL FAILURE AND GLAUCOMA | SMITHKLINE BEECHAM CORP (US) | 1996-06-25 | — | — | US | disclosed |
| US-5444080-A | Hypotensive agents | SMITHKLINE BEECHAM CORPORATION (US) | 1995-08-22 | — | — | US | disclosed |
| EP-0541705-A4 | SUBSTITUTED 1H-IMIDAZOL-5-YL)ALKANOIC ACIDS | — | 1993-11-10 | — | — | EP | disclosed |
| US-5234917-A | Hypotensive agent, treatment of renal failure or glaucoma | SMITHKLINE BEECHAM CORPORATION | 1993-08-10 | — | — | US | disclosed |
| EP-0541705-A1 | SUBSTITUTED 1H-IMIDAZOL-5-YL]ALKANOIC ACIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-05-19 | — | — | EP | disclosed |
| WO-1992002510-A1 | SUBSTITUTED [1H-IMIDAZOL-5-YL]ALKANOIC ACIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1992-02-20 | — | — | WO | disclosed |