SCHEMBL8954836

SCHEMBL8954836

N=C(N)c1cccc(C[C@H](NS(=O)(=O)c2ccc3ccccc3c2)C(=O)N2CCC[C@H]2C(=O)C(CCN)C(=O)O)c1

nearest known ligand 0.68

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ F10 P00742 14/20 0.68
▸ PLAU P00749 6/20 0.67
▸ PLG P00747 6/20 0.65
▸ ST14 Q9Y5Y6 4/20 0.65
▸ F2 P00734 3/20 0.65
▸ HPN P05981 1/20 0.64
▸ HGFAC Q04756 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8955017 0.98 F10 (0.69) F10PLAUPLGST14F2
SCHEMBL8954780 0.93 F10 (0.66) F10PLAUPLGST14F2
SCHEMBL8954695 0.90 F10 (0.75) F10PLAUPLGST14F2
SCHEMBL8954768 0.90 F10 (0.75) F10PLAUPLGST14F2
SCHEMBL8954681 0.90 F10 (0.75) F10PLAUPLGST14F2
SCHEMBL8954726 0.90 F10 (0.75) F10PLAUPLGST14F2
Hydrochloric Acid SCHEMBL8954848 0.89 F10 (0.74) F10PLAUPLGST14F2
SCHEMBL30583119 0.88 F10 (0.76) F10PLAUPLGST14F2
SCHEMBL8954741 0.87 F10 (0.81) F10PLAUPLGST14F2
SCHEMBL8954840 0.82 PLG (0.65) F10PLAUPLGST14F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5518735-A ANTICOAGULANTS ADMINISTERED BY MOUTH PENTAPHARM AG (CH) 1996-05-21 — — US disclosed
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