SCHEMBL8954841

SCHEMBL8954841

Nc1cccc(C[C@H](NS(=O)(=O)c2ccc3ccccc3c2)C(=O)N2CCC[C@H]2C(=O)O)c1

nearest known ligand 0.59

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
F10 P00742 13/20 0.59
PLAU P00749 5/20 0.56
F2 P00734 3/20 0.56
PLG P00747 6/20 0.55
ST14 Q9Y5Y6 4/20 0.55
HPN P05981 1/20 0.55
HGFAC Q04756 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8654566 0.92 F2 (0.59) F10PLAUF2PLGST14
SCHEMBL8654561 0.92 F2 (0.59) F10PLAUF2PLGST14
SCHEMBL8955035 0.92 F2 (0.62) F10PLAUF2PLGST14
SCHEMBL9710642 0.90 F2 (0.69) F10PLAUF2PLGST14
SCHEMBL9710089 0.89 F2 (0.61) F10PLAUF2PLGST14
SCHEMBL8954654 0.89 F10 (0.59) F10PLAUF2PLGST14
SCHEMBL8954942 0.89 F10 (0.69) F10PLAUF2PLGST14
SCHEMBL8954726 0.89 F10 (0.75) F10PLAUF2PLGST14
SCHEMBL8954768 0.89 F10 (0.75) F10PLAUF2PLGST14
SCHEMBL8954681 0.89 F10 (0.75) F10PLAUF2PLGST14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5518735-A ANTICOAGULANTS ADMINISTERED BY MOUTH PENTAPHARM AG (CH) 1996-05-21 US disclosed
EP-0511347-A1 META-SUBSTITUTED PHENYL ALANINE DERIVATIVES Pentapharm A.G. (CH) 1992-11-04 EP disclosed
WO-1992008709-A1 META-SUBSTITUTED PHENYL ALANINE DERIVATIVES PENTAPHARM AG (CH) 1992-05-29 WO disclosed