Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 14/20 | 0.51 |
| ▸ | PLG | P00747 | 8/20 | 0.46 |
| ▸ | PROC | P04070 | 1/20 | 0.45 |
| ▸ | ST14 | Q9Y5Y6 | 4/20 | 0.45 |
| ▸ | HPN | P05981 | 1/20 | 0.45 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 5/20 | 0.45 |
| ▸ | F2 | P00734 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8954880 | 0.99 | F10 (0.52) | F10PLGPROCST14HPN | |
| SCHEMBL8954816 | 0.89 | F10 (0.39) | F10PLGF2 | |
| Iodide SCHEMBL9666229 | 0.89 | F10 (0.49) | F10PLGPROCST14HPN | |
| SCHEMBL8954679 | 0.88 | F10 (0.43) | F10PLGPROCST14HPN | |
| SCHEMBL9664145 | 0.88 | F10 (0.50) | F10PLGPROCST14HPN | |
| SCHEMBL8954682 | 0.86 | ALOX5AP (0.38) | F10F2 | |
| Hydrochloric Acid SCHEMBL8954922 | 0.85 | F10 (0.51) | F10PLGPROCST14HPN | |
| SCHEMBL8954706 | 0.84 | F10 (0.52) | F10PLGPROCST14HPN | |
| SCHEMBL8954584 | 0.84 | F10 (0.39) | F10PLGST14PLAUF2 | |
| SCHEMBL8954767 | 0.81 | F10 (0.50) | F10PLGPROCST14HPN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5518735-A | ANTICOAGULANTS ADMINISTERED BY MOUTH | PENTAPHARM AG (CH) | 1996-05-21 | — | — | US | disclosed |