SCHEMBL8955241

SCHEMBL8955241

C[Si](C)(O)C1CCCCCC1

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.34
NR1H3 Q13133 1/20 0.34
GAA P10253 1/20 0.31
PKM P14618 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
CES2 O00748 1/20 0.30
CES1 P23141 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1776986 1.00 NR1H2 (0.34) NR1H2NR1H3GAAPKMTDP1
SCHEMBL8955133 1.00 NR1H2 (0.34) NR1H2NR1H3GAAPKMTDP1
SCHEMBL2920466 0.97
SCHEMBL8955157 0.90
SCHEMBL13679151 0.83
SCHEMBL11416727 0.81 NR1H2 (0.34) NR1H2NR1H3GAAPKMTDP1
SCHEMBL3898908 0.81 NR1H2 (0.34) NR1H2NR1H3GAAPKMTDP1
SCHEMBL2022755 0.78 TSHR (0.32) NR1H2NR1H3TSHR
SCHEMBL2294587 0.75 NR1H2 (0.32) NR1H2NR1H3
SCHEMBL94046 0.73 NR1H2 (0.32) NR1H2NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5484685-A Naphthalocyanine derivatives, production thereof, optical recording medium using the same, and production thereof HITACHI, LTD. (JP) 1996-01-16 US disclosed
EP-0366440-B1 Naphthalocyanine derivatives, production thereof, optical recording medium using the same, and production thereof HITACHI CHEMICAL CO LTD (JP) 1994-06-08 EP disclosed
EP-0366440-A2 Naphthalocyanine derivatives, production thereof, optical recording medium using the same, and production thereof Hitachi Chemical Co., Ltd. (JP) 1990-05-02 EP disclosed