SCHEMBL8955355

SCHEMBL8955355

CCCCO[Si](O)(OCCCC)C1CCCCC1

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.38
NAAA Q02083 3/20 0.35
TSHR P16473 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
CNR2 P34972 3/20 0.32
EPHX1 P07099 2/20 0.31
SIGMAR1 Q99720 1/20 0.31
CNR1 P21554 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8955090 1.00 CYP1A2 (0.38) CYP1A2NAAATSHRSMN1; SMN2CNR2
SCHEMBL8955062 1.00 CYP1A2 (0.38) CYP1A2NAAATSHRSMN1; SMN2CNR2
SCHEMBL8955073 0.98 TSHR (0.35) CYP1A2NAAATSHRSMN1; SMN2CNR2
SCHEMBL8955351 0.94 TSHR (0.35) CYP1A2NAAATSHRSMN1; SMN2
SCHEMBL8955660 0.90 TSHR (0.38) TSHRSMN1; SMN2
SCHEMBL8955780 0.88 CYP1A2 (0.31) CYP1A2NAAA
SCHEMBL8955194 0.88 CYP1A2 (0.31) CYP1A2NAAA
SCHEMBL8955141 0.88 CYP1A2 (0.31) CYP1A2NAAA
SCHEMBL8955131 0.86 CA1 (0.30)
SCHEMBL8955473 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5484685-A Naphthalocyanine derivatives, production thereof, optical recording medium using the same, and production thereof HITACHI, LTD. (JP) 1996-01-16 US disclosed
EP-0366440-B1 Naphthalocyanine derivatives, production thereof, optical recording medium using the same, and production thereof HITACHI CHEMICAL CO LTD (JP) 1994-06-08 EP disclosed
EP-0366440-A2 Naphthalocyanine derivatives, production thereof, optical recording medium using the same, and production thereof Hitachi Chemical Co., Ltd. (JP) 1990-05-02 EP disclosed