Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.51 |
| ▸ | CNR1 | P21554 | 5/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | HTR1B | P28222 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16417099 | 0.95 | CNR2 (0.55) | CNR2CNR1CYP2C9HTR1BHTR1D | |
| SCHEMBL9700638 | 0.91 | CNR2 (0.58) | CNR2CNR1CYP2C9HTR1BHTR1D | |
| SCHEMBL2924471 | 0.89 | CYP2C9 (0.59) | CNR2CNR1CYP2C9HTR1BCYP1A2 | |
| SCHEMBL30503960 | 0.89 | CYP2C9 (0.59) | CNR2CNR1CYP2C9HTR1BCYP1A2 | |
| 1,4-Butanediol SCHEMBL9011589 | 0.88 | HTR1B (0.64) | CNR2CNR1HTR1BHTR1DSLC6A4 | |
| 1,5-Pentanediol SCHEMBL9011746 | 0.87 | HTR1B (0.62) | CNR2CNR1HTR1BHTR1DSLC6A4 | |
| 1,6-Hexanediol SCHEMBL9011607 | 0.87 | HTR1B (0.62) | CNR2CNR1HTR1BHTR1DSLC6A4 | |
| SCHEMBL16519470 | 0.85 | CYP2C9 (0.60) | CNR2CNR1CYP2C9HTR1BCYP1A2 | |
| SCHEMBL6938193 | 0.85 | CNR1 (0.57) | CNR2CNR1CYP2C9HTR1BCYP1A2 | |
| SCHEMBL347409 | 0.85 | CNR1 (0.57) | CNR2CNR1CYP2C9HTR1BCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516767-A | PRODRUG AS HYPOGLYCEMIC AGENT | SANDOZ LTD. (CH) | 1996-05-14 | — | — | US | disclosed |
| US-5412137-A | Hypoglycemic agents | SANDOZ LTD. (CH) | 1995-05-02 | — | — | US | disclosed |