Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21344909 | 0.91 | MEN1 (0.45) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL12561571 | 0.91 | TSHR (0.42) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL14898427 | 0.84 | CYP4F2 (0.42) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL25939787 | 0.83 | HRH3 (0.44) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL13804946 | 0.81 | TSHR (0.42) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL7964566 | 0.80 | TSHR (0.56) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL14586412 | 0.80 | HRH3 (0.46) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL25884127 | 0.80 | HRH3 (0.46) | TSHRHRH3 | |
| SCHEMBL6047745 | 0.80 | MEN1 (0.55) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL8936938 | 0.80 | MEN1 (0.55) | MEN1KMT2ATHRBHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516767-A | PRODRUG AS HYPOGLYCEMIC AGENT | SANDOZ LTD. (CH) | 1996-05-14 | — | — | US | disclosed |
| US-5412137-A | Hypoglycemic agents | SANDOZ LTD. (CH) | 1995-05-02 | — | — | US | disclosed |