Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.41 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.41 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.41 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4599498 | 0.95 | USP2 (0.50) | USP2HTTMEN1KMT2ATHRB | |
| SCHEMBL8956138 | 0.95 | USP2 (0.50) | USP2HTTMEN1KMT2ATHRB | |
| SCHEMBL18110421 | 0.91 | USP2 (0.52) | USP2HTTMEN1KMT2ATHRB | |
| SCHEMBL25757747 | 0.89 | HTT (0.53) | USP2HTTMEN1KMT2ATHRB | |
| SCHEMBL8955582 | 0.89 | USP2 (0.47) | USP2HTTMEN1KMT2ATHRB | |
| SCHEMBL25757742 | 0.89 | HTT (0.53) | USP2HTTMEN1KMT2ATHRB | |
| SCHEMBL27693785 | 0.87 | USP2 (0.52) | USP2HTTMEN1KMT2ATHRB | |
| SCHEMBL13459002 | 0.86 | MEN1 (0.60) | USP2HTTMEN1KMT2ATHRB | |
| SCHEMBL29356122 | 0.86 | MEN1 (0.60) | USP2HTTMEN1KMT2ATHRB | |
| SCHEMBL29053365 | 0.86 | MEN1 (0.60) | USP2HTTMEN1KMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516767-A | PRODRUG AS HYPOGLYCEMIC AGENT | SANDOZ LTD. (CH) | 1996-05-14 | — | — | US | disclosed |
| US-5412137-A | Hypoglycemic agents | SANDOZ LTD. (CH) | 1995-05-02 | — | — | US | disclosed |