Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 3/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | DHFR | P00374 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL292109 | 0.94 | HSPA5 (0.50) | HSPA5HIF1ACYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL39543 | 0.87 | HSPA5 (0.65) | HSPA5HIF1ACYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL28384212 | 0.85 | HSPA5 (0.53) | HSPA5HIF1ACYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL30464059 | 0.85 | HSPA5 (0.53) | HSPA5HIF1ACYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL12620490 | 0.84 | HSPA5 (0.77) | HSPA5HIF1ACYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL9475140 | 0.84 | HSPA5 (0.70) | HSPA5HIF1ACYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL9817016 | 0.83 | HSPA5 (0.60) | HSPA5HIF1ACYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL8955916 | 0.81 | HSPA5 (0.58) | HSPA5HIF1ACYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL8772273 | 0.81 | MEN1 (0.49) | HSPA5HIF1ACYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL11248433 | 0.80 | HSPA5 (0.76) | HSPA5HIF1ACYP2C9CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0323409-B1 | Polyolefin compositions stabilized with long chain N,N-dialkylhydroxylamines | CIBA GEIGY AG (CH) | 1996-01-03 | — | — | EP | disclosed |