Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8956601 | 0.81 | USP2 (0.35) | USP2TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL13687952 | 0.80 | KMT2A (0.54) | USP2TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL8749749 | 0.79 | — | — | |
| SCHEMBL8956526 | 0.79 | USP2 (0.39) | USP2TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL2019186 | 0.78 | USP2 (0.37) | USP2TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL2019183 | 0.78 | USP2 (0.37) | USP2TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL22183413 | 0.78 | MEN1 (0.36) | USP2TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL929185 | 0.77 | — | — | |
| SCHEMBL9593659 | 0.77 | — | — | |
| SCHEMBL8956871 | 0.76 | CACNA1B (0.49) | ALDH1A1MAPTLMNAANPEPDNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514282-B1 | Alkylamino mercaptoalkylamides or salts thereof acceptable for cosmetic use, their use as a reducing agent and a process for the permanent deformation of hair | OREAL (FR) | 1996-04-10 | — | — | EP | claimed |
| US-5583257-A | REDUCING AGENTS FOR PERMANENT HAIR; ODORLESS | L'OREAL (FR) | 1996-12-10 | — | — | US | disclosed |
| US-5449805-A | Permanent waves for hair | L'OREAL (FR) | 1995-09-12 | — | — | US | disclosed |
| US-5334377-A | Reduction of the disulfide bond of keratin; the oxidation | L'OREAL (FR) | 1994-08-02 | — | — | US | disclosed |