Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 2/20 | 0.48 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8956491 | 0.88 | GGPS1 (0.51) | GGPS1 | |
| SCHEMBL8956499 | 0.86 | GGPS1 (0.49) | GGPS1 | |
| SCHEMBL8956415 | 0.86 | GGPS1 (0.61) | GGPS1CNR1CNR2 | |
| SCHEMBL8956417 | 0.86 | GGPS1 (0.61) | GGPS1CNR1CNR2 | |
| SCHEMBL8956899 | 0.86 | GGPS1 (0.61) | GGPS1CNR1CNR2 | |
| SCHEMBL8956369 | 0.85 | GGPS1 (0.57) | GGPS1S1PR2S1PR1S1PR3LPAR2 | |
| SCHEMBL8956302 | 0.84 | GGPS1 (0.47) | GGPS1 | |
| SCHEMBL8956427 | 0.84 | GGPS1 (0.47) | GGPS1 | |
| SCHEMBL8956430 | 0.84 | GGPS1 (0.49) | GGPS1 | |
| SCHEMBL8956529 | 0.83 | GGPS1 (0.48) | GGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0374513-B1 | Novel bis-arylphosphate ester antagonists of platelet activating factor | AMERICAN CYANAMID CO (US) | 1996-01-10 | — | — | EP | disclosed |
| US-5328901-A | Respiratory system disorders | AMERICAN CYANAMID COMPANY (US) | 1994-07-12 | — | — | US | disclosed |
| US-5231091-A | Antihistamines, anaphylactic, respiratory system disorders, cardiovascular disorders ans septic shock | AMERICAN CYANAMID COMPANY (US) | 1993-07-27 | — | — | US | disclosed |
| US-5147864-A | Bronchodilator agent, antianaphylactic agent, antishock agent, cardiotonic agent and anticarcinogenic agent | AMERICAN CYANAMID COMPANY (US) | 1992-09-15 | — | — | US | disclosed |
| US-4983592-A | Bis-arylphosphate ester antagonists of platelet activating factor | AMERICAN CYANAMID CO. (US) | 1991-01-08 | — | — | US | disclosed |
| EP-0374513-A2 | Novel bis-arylphosphate ester antagonists of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1990-06-27 | — | — | EP | disclosed |