Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.80 |
| ▸ | CA4 | P22748 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28407128 | 0.95 | CA1 (0.73) | CA1CA4LMNATSHRFFAR3 | |
| Acetic Acid SCHEMBL51 | 0.95 | — | — | |
| Acetic Acid SCHEMBL5082363 | 0.95 | CA1 (0.89) | CA1CA4LMNATSHRFFAR3 | |
| Acetic Acid SCHEMBL19671 | 0.95 | CA1 (0.89) | CA1CA4LMNATSHRFFAR3 | |
| Acetic Acid SCHEMBL10578328 | 0.95 | CA1 (0.89) | CA1CA4LMNATSHRFFAR3 | |
| Acetic Acid SCHEMBL11103091 | 0.90 | CA1 (0.80) | CA1CA4LMNATSHRFFAR3 | |
| Acetic Acid SCHEMBL8853012 | 0.90 | CA1 (0.80) | CA1CA4LMNATSHRFFAR3 | |
| Acetic Acid SCHEMBL10179054 | 0.90 | CA1 (0.80) | CA1CA4LMNATSHRFFAR3 | |
| Acetic Acid SCHEMBL11134030 | 0.90 | — | — | |
| Acetic Acid SCHEMBL9718803 | 0.90 | CA1 (0.80) | CA1CA4LMNATSHRFFAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114931068-A | Soil improvement method for intercropping insect-repelling volatile grass seeds in macadamia nut garden | 广西南亚热带农业科学研究所 | 2022-08-23 | — | — | CN | claimed |
| US-20140343160-A1 | ADHESIVE MIXTURE FOR TRANSDERMAL DELIVERY OF HIGHLY PLASTICIZING DRUGS | BERTEK, INC. | 2014-11-20 | — | — | US | claimed |
| US-20130018078-A1 | ADHESIVE MIXTURE FOR TRANSDERMAL DELIVERY OF HIGHLY PLASTICIZING DRUGS | MYLAN TECHNOLOGIES INC. (US) | 2013-01-17 | — | — | US | claimed |
| US-20100040690-A1 | Adhesive mixture for transdermal delivery of highly plasticizing drugs | MYLAN TECHNOLOGIES, INC. | 2010-02-18 | — | — | US | claimed |
| US-7070808-B2 | Adhesive mixture for transdermal delivery of highly plasticizing drugs | MYLAN TECHNOLOGIES, INC. (US) | 2006-07-04 | — | — | US | claimed |
| EP-1561461-A2 | Adhesive mixture for transdermal delivery of highly plasticizing drugs | MYLAN TECHNOLOGIES, INC. (US) | 2005-08-10 | — | — | EP | claimed |
| US-20040137046-A1 | such as selegiline and/or the use of protonated forms of various drugs; an adhesive, the drug in protonated form, a nonaqueous solvent that dissolves said drug in either protonated or unprotonated form, and a biocompatible deprotonating agent | MYLAN TECHNOLOGIES, INC. | 2004-07-15 | — | — | US | claimed |
| US-20020150613-A1 | Patches; sustained release drug delivery | MYLAN TECHNOLOGIES, INC. | 2002-10-17 | — | — | US | claimed |
| US-20010006628-A1 | Comprising an adhesive, drug in protonated form, a nonaqueous solvent capable of dissolving nonprotonated and protonated forms of the drug, and a biocompatible deprotonating agent to deprotonate the drug without irritating the skin | MYLAN TECHNOLOGIES, INC. | 2001-07-05 | — | — | US | claimed |
| EP-0887075-A2 | Adhesive mixture for transdermal delivery of highly plasticizing drugs | BERTEK, INC. (US) | 1998-12-30 | — | — | EP | claimed |
| CN-114931068-A | Soil improvement method for intercropping insect-repelling volatile grass seeds in macadamia nut garden | 广西南亚热带农业科学研究所 | 2022-08-23 | — | — | CN | disclosed |
| CN-114558534-A | Preparation method of high-electric-conductivity and high-heat-conductivity flaky gallium-indium-doped AZO, flaky gallium-indium-doped AZO and composite material | 西安安聚德纳米科技有限公司 | 2022-05-31 | — | — | CN | disclosed |
| US-20180049999-A1 | COMPOSITIONS AND METHODS OF TREATMENT OF BREAST DISORDERS AND ESTROGEN-RELATED DISORDERS | ATOSSA THERAPEUTICS, INC. | 2018-02-22 | — | — | US | disclosed |
| EP-3283061-A1 | COMPOSITIONS AND METHODS OF TREATMENT OF BREAST DISORDERS AND ESTROGEN-RELATED DISORDERS | Atossa Genetics Inc. (US) | 2018-02-21 | — | — | EP | disclosed |
| CN-107708678-A | Treat the composition and method of disorder of breast and estrogen associated conditions | 阿托萨遗传学公司 | 2018-02-16 | — | — | CN | disclosed |
| US-20040137046-A1 | such as selegiline and/or the use of protonated forms of various drugs; an adhesive, the drug in protonated form, a nonaqueous solvent that dissolves said drug in either protonated or unprotonated form, and a biocompatible deprotonating agent | MYLAN TECHNOLOGIES, INC. | 2004-07-15 | — | — | US | disclosed |
| US-20020150613-A1 | Patches; sustained release drug delivery | MYLAN TECHNOLOGIES, INC. | 2002-10-17 | — | — | US | disclosed |
| US-20010006628-A1 | Comprising an adhesive, drug in protonated form, a nonaqueous solvent capable of dissolving nonprotonated and protonated forms of the drug, and a biocompatible deprotonating agent to deprotonate the drug without irritating the skin | MYLAN TECHNOLOGIES, INC. | 2001-07-05 | — | — | US | disclosed |
| EP-0887075-A2 | Adhesive mixture for transdermal delivery of highly plasticizing drugs | BERTEK, INC. (US) | 1998-12-30 | — | — | EP | disclosed |
| US-4661205-A | ALUMINUM, ZINC OR MOLYBDENUM | SCOTT PAPER COMPANY (US) | 1987-04-28 | — | — | US | disclosed |