Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 10/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28921029 | 1.00 | — | — | |
| SCHEMBL324551 | 0.88 | — | — | |
| SCHEMBL14499693 | 0.88 | — | — | |
| SCHEMBL9019587 | 0.87 | GSR (0.41) | GSRCA2ALDH1A1MAPT | |
| SCHEMBL4219645 | 0.87 | GSR (0.41) | GSRCA2ALDH1A1MAPT | |
| SCHEMBL9019582 | 0.87 | GSR (0.41) | GSRCA2ALDH1A1MAPT | |
| SCHEMBL4531968 | 0.87 | GSR (0.41) | GSRCA2ALDH1A1MAPT | |
| SCHEMBL11060513 | 0.87 | GSR (0.41) | GSRCA2ALDH1A1MAPT | |
| Ammonia Solution, Strong SCHEMBL10427644 | 0.86 | GSR (0.54) | GSRCA2ALDH1A1MAPT | |
| SCHEMBL3804843 | 0.86 | GSR (0.54) | GSRCA2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0689435-A1 | USE OF SUBSTITUTED ALKYL NITRATES FOR THE TREATMENT OF PATHOLOGICALLY INCREASED INTRA-OCULAR PRESSURE | BYK NEDERLAND BV (NL) | 1996-01-03 | — | — | EP | claimed |
| WO-1994021248-A1 | USE OF SUBSTITUTED ALKYL NITRATES FOR THE TREATMENT OF PATHOLOGICALLY INCREASED INTRA-OCULAR PRESSURE | BYK NEDERLAND BV (NL) | 1994-09-29 | — | — | WO | claimed |
| US-5049694-A | Cardiovascular disorders | CEDONA PHARMACEUTICALS B.V. (NL) | 1991-09-17 | — | — | US | disclosed |
| EP-0359335-A2 | Pharmaceutical composition having relaxing activity which contains a nitrate ester as active substance | CEDONA PHARMACEUTICALS B.V. (NL) | 1990-03-21 | — | — | EP | disclosed |